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Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.

199 p.

Idioma:	English
Publicación:	2019
Materia:	antibiotics bacteriology molecular biology of microorganisms antibióticos bactereología biología molecular de microorganismos
Acceso electrónico:	http://hdl.handle.net/10810/32465

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id	oai:addi.ehu.eus:10810-32465
recordtype	addi
spelling	oai:addi.ehu.eus:10810-324652022-09-30T17:53:45Zcom_10810_12140Doktorego Tesiak;;Tesis Doctoralescom_10810_91IKERKUNTZA;;INVESTIGACIÓNcol_10810_12143DT-Bizitzaren Zientziak;;TD-Ciencias de la Vida Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia. Cerezales González, Mónica Higgins, Paul G. Gallego Andrés, Lucía antibiotics bacteriology molecular biology of microorganisms antibióticos bactereología biología molecular de microorganismos 199 p. Acinetobacter baumannii is a Gram-negative opportunistic pathogen causing serious hospital-acquired infections and it has been recently positioned as a priority pathogen by the World Health Organization. It has been described causing outbreaks worlwide and its antimicrobial resistance has been worryingly rising in recent times. A. baumannii usually causes infections such as ventilator associated pneumonia, septicaemia, urinary tract infections, wound infections or meningitis, especially in compromised patient groups such as those admitted to ICU and elderly patients, increasing the mortality rates and hospitalization costs.Other species belonging to the A. baumannii group are being described more often lately as causing infections and sometimes related to antimicrobial resistance determinants.This work is focused in the study of A. baumannii isolates recovered from clinical samples in the two main hospitals of Cochabamba, Bolivia, Hospital Materno-Infantil and Hospital Viedma.The present work is divided in four sections.Sections 1. The epidemiology and antibiotic resistance genes were studied in A. baumannii isolates from a Children Hospital.Section 2. We studied molecular epidemiology by cgMLST and resistome of CRAb isolates from the two main hospitals of the city of Cochabamba. Section 3. Study of the mobile genetic elements encoding antibiotic resistance genes in A. baumannii isolates belonging to different ICs.Section 4. Identification of Acinetobacter seifertii, an A. baumannii group member, isolated from both hospitals in Cochabamba. 2019-04-15T10:32:13Z 2019-04-15T10:32:13Z 2018-12-05 2018-12-05 info:eu-repo/semantics/doctoralThesis http://hdl.handle.net/10810/32465 780973 17390 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc/3.0/es/ Atribución-NoComercial 3.0 España (cc)2018 MONICA CEREZALES GONZALEZ (cc by-nc 4.0) application/pdf
external_data_source	Addi
institution	Digital
collection	Addi
language	English
topic	antibiotics bacteriology molecular biology of microorganisms antibióticos bactereología biología molecular de microorganismos
spellingShingle	antibiotics bacteriology molecular biology of microorganisms antibióticos bactereología biología molecular de microorganismos Cerezales González, Mónica Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.
description	199 p.
author_additional	Higgins, Paul G.
author	Cerezales González, Mónica
title	Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.
title_short	Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.
title_full	Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.
title_fullStr	Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.
title_full_unstemmed	Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.
title_sort	molecular characterization of acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in bolivia.
publishDate	2019
url	http://hdl.handle.net/10810/32465
_version_	1758548758602186752

Molecular characterization of Acinetobacter spp. and their antibiotic resistance mobilome from clinical isolates collected in Bolivia.

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