Hypomethylation of paternal DNA in the late mouse zygote is not essential for development
Global demethylation of DNA which marks the onset of development occurs asynchronously in the mouse; paternal DNA is demethylated at the the zygote stage, whereas maternal DNA is demethylated later in development. The biological function of such asymmetry and its underlying mechanisms are currently...
Número de control: | 382917 Artículo de revista |
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Publicado en: International journal of developmental biology Vol. 52, N. 2-3 (2008) |